Linked Life Data

310559

Source:http://linkedlifedata.com/resource/pubmed/id/310559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1979-3-24
pubmed:abstractText
The distribution of eating, drinking and body weight changes during the 24 hr day were examined following brain 5-HT depletion with p-chloroamphetamine (PCA). Following a baseline period, measurements of food and water intakes and body weights were recorded 1, 2, 3, 6, 12, 20 and 24 hr following PCA, 5.0 mg/kg, or saline. Other animals were pretreated with fluoxetine, 10.0 mg/kg, prior to either PCA or saline in an attempt to block the PCA effects. The results indicate acute hypophagia, hypodipsia, and body weight losses. These decreases were not influenced by the time of day when PCA was administered. Pretreatment with fluoxetine enhanced rather than blocked these effects. No long term changes in ingestive behavior were seen. These results are discussed with respect to the possible role of 5-HT in the control of ingestive behavior.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
677-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Synergistic action of p-chloroamphetamine and fluoxetine on food and water consumption patterns in the rat.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.