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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1987-3-30
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pubmed:abstractText |
Pure red cell aplasia (PRCA) is an unusual complication of chronic lymphoproliferative disorders. A patient with T-cell chronic lymphocytic leukemia (T-CLL) had severe anemia and neutropenia. Initial in vitro studies demonstrated no evidence of T-cell suppression of erythropoiesis. Sequential bone marrow examinations demonstrated progressive red cell aplasia. In vitro studies showed that the T-cells from the patient suppressed allogeneic but not autologous BFU-E. Treatment with antithymocyte globulin (ATG) reduced circulating leukemic cells and produced a definite but transient improvement in erythropoiesis.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0361-8609
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
285-91
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3103427-Adult,
pubmed-meshheading:3103427-Antibodies, Monoclonal,
pubmed-meshheading:3103427-Antigens, Surface,
pubmed-meshheading:3103427-Antilymphocyte Serum,
pubmed-meshheading:3103427-Colony-Forming Units Assay,
pubmed-meshheading:3103427-Humans,
pubmed-meshheading:3103427-Leukemia, Lymphoid,
pubmed-meshheading:3103427-Male,
pubmed-meshheading:3103427-Red-Cell Aplasia, Pure,
pubmed-meshheading:3103427-Rosette Formation,
pubmed-meshheading:3103427-T-Lymphocytes
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pubmed:year |
1987
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pubmed:articleTitle |
Transient response of pure red cell aplasia to anti-thymocyte globulin in a patient with T-cell chronic lymphocytic leukemia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
|