Linked Life Data

3100704

Source:http://linkedlifedata.com/resource/pubmed/id/3100704

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1987-3-6
pubmed:abstractText
In order to obtain some clues to the mechanism of follicular development, we studied sequential changes in circulatory hormone from spontaneous abortion up to the next ovulation in 11 women. In addition, morphological analysis of the follicles was performed in the ovarian tissue obtained from 4 pregnant women and another 4 women with polycystic ovarian syndrome (PCO). Blood was collected every 2-4 days and the serum samples were analyzed for HCG (LH), FSH, progesterone and estradiol by radioimmunoassay (RIA). Whole ovaries or the tissue obtained by ovarian wedge resection were sectioned serially at 2.5 micrometers. Every 13th slice was stained and examined under a light microscope. The present data were summarized as follows. A dominant follicle started to grow when LH.HCG levels declined to approximately 120 mIU l and FSH increased slightly. The largest nonatretic follicle seen in pregnancy or PCO was comparable with that seen in the late luteal phase of a normal cycle. The atretic rate of middle sized follicles (2.0 less than or equal to approximately less than 4.0 mm in diameter) was significantly higher in PCO than that seen in normal or pregnant women. These data indicate that the hormonal milieu of pregnancy or PCO does not interfere with the follicular development up to the stage of the largest nonatretic follicle seen in the late luteal phase of a normal cycle. This sized follicle grows to a dominant follicle within a short period under a minor stimulus by FSH.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0300-9165
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2195-200
pubmed:dateRevised
2011-7-29
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
[Follicular development in pregnancy and the polycystic ovarian syndrome].
pubmed:publicationType
Journal Article, English Abstract