|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
1987-2-17
|
|
pubmed:abstractText |
Genomic DNAs from dimethylbenzanthracene-induced BALB/c mouse mammary tumors arising from the transplantable hyperplastic outgrowth (HPO) line designated DI/UCD transformed NIH 3T3 cells upon transfection. Transforming activity was attributed to the presence of activated Harvey ras-1 oncogenes containing an A----T transversion at the middle adenosine nucleotide in codon 61. DNAs from untreated DI/UCD HPO cells and radiation-induced and spontaneous mammary tumors from the DI/UCD HPO line failed to transform NIH 3T3 cells. The results indicated that the mutation activation of Harvey ras-1 oncogenes was specific to dimethylbenzanthracene treatment in the mouse mammary tumor system.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-1195397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-194704,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-3014349,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-3923365,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-4298252,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-4301594,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-4311120,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-4705382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6089200,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6089339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6190194,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6253666,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6290897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6302839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6306478,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6315214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6322298,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6409397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6431299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6572002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-6582476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-7051963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-7094016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3099168-881736
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0270-7306
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
6
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
4104-8
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:3099168-9,10-Dimethyl-1,2-benzanthracene,
pubmed-meshheading:3099168-Animals,
pubmed-meshheading:3099168-Cell Transformation, Neoplastic,
pubmed-meshheading:3099168-Cells, Cultured,
pubmed-meshheading:3099168-Mammary Neoplasms, Experimental,
pubmed-meshheading:3099168-Mice,
pubmed-meshheading:3099168-Mice, Inbred Strains,
pubmed-meshheading:3099168-Mutation,
pubmed-meshheading:3099168-Oncogenes,
pubmed-meshheading:3099168-Polymorphism, Genetic
|
|
pubmed:year |
1986
|
|
pubmed:articleTitle |
Specific activation of the cellular Harvey-ras oncogene in dimethylbenzanthracene-induced mouse mammary tumors.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
