|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0000975,
umls-concept:C0006675,
umls-concept:C0017262,
umls-concept:C0022022,
umls-concept:C0024264,
umls-concept:C0029016,
umls-concept:C0070750,
umls-concept:C0086418,
umls-concept:C0086661,
umls-concept:C0087140,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0205374,
umls-concept:C0332283,
umls-concept:C1948023,
umls-concept:C2911684
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
1986-12-29
|
|
pubmed:abstractText |
After stimulation of human lymphocytes by 12-0 tetradecanoyl phorbol acetate (TPA) and by the calcium ionophore A23187 an early transient expression of proto-oncogene fos followed by an expression of c-myc is observed, as has been described in rodent fibroblast stimulated by growth factors. This observation suggests a direct role of protein Kinase C and of calcium flux an the induction of cellular oncogenes fos and myc that may be associated with the early steps of activation and proliferation of lymphocytes.
|
|
pubmed:language |
fre
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0764-4469
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
303
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
445-7
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1986
|
|
pubmed:articleTitle |
[Stimulation of human lymphocytes by phorbol acetate and a calcium ionophore induces an early transient expression of the c-fos oncogene followed by c-myc].
|
|
pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|
