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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1986-12-17
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pubmed:abstractText |
Previous reconstitution studies in irradiated mice distinguished Ly-1 B from other B cells. The predominant B cell populations in spleen and lymph node are readily reconstituted from progenitors present in adult bone marrow. Ly-1 B cells, in contrast, are reconstituted from cells in peritoneum rather than bone marrow. Further studies, presented here, demonstrate that Ly-1 B populations are reconstituted from peritoneal cells that already express both surface immunoglobulin (IgM) and Ly-1, that is, Ly-1 B. Such cells reconstitute and maintain the Ly-1 B population in irradiated recipients for at least 6 months.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0014-2980
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1313-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3095127-Animals,
pubmed-meshheading:3095127-Antigens, Ly,
pubmed-meshheading:3095127-B-Lymphocytes,
pubmed-meshheading:3095127-Cell Separation,
pubmed-meshheading:3095127-Flow Cytometry,
pubmed-meshheading:3095127-Hematopoietic Stem Cells,
pubmed-meshheading:3095127-Immunoglobulin Light Chains,
pubmed-meshheading:3095127-Immunoglobulins,
pubmed-meshheading:3095127-Lymphocyte Activation,
pubmed-meshheading:3095127-Mice,
pubmed-meshheading:3095127-Mice, Inbred CBA,
pubmed-meshheading:3095127-Peritoneal Cavity,
pubmed-meshheading:3095127-Spleen
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pubmed:year |
1986
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pubmed:articleTitle |
Immunoglobulin-bearing B cells reconstitute and maintain the murine Ly-1 B cell lineage.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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