Linked Life Data

3093021

Source:http://linkedlifedata.com/resource/pubmed/id/3093021

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-11-20
pubmed:abstractText
Forearm bone mineral content (BMC), an index of skeletal mineralization, and lean body mass (LBM), an index of the muscle mass in the body, were calculated in 574 healthy, white subjects, aged 20-89 years. In women, there was no significant change in BMC with age until the menopause. Thereafter, a significant decline averaging 15% per decade was found up to the age of 70 years, after which it was 10% per decade. In men, there was a significant overall decline of about 4% per decade from the age of 20. When BMC was corrected for LBM, the age-related fall in men disappeared, while remaining without a significant trend in premenopausal women. This was, however, not the case in women after the menopause, where a significant decline of about 12% per decade was noted. These data clearly demonstrate that the major contribution to the well-known bone loss in postmenopausal women is not a simple age-related phenomenon. The development of osteoporosis must be due to some additional bone-diminishing effect on the female skeleton, most likely the absence of estrogen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0171-967X
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
123-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Is postmenopausal bone loss an age-related phenomenon?
pubmed:publicationType
Journal Article, Comparative Study