Linked Life Data

3092597

Source:http://linkedlifedata.com/resource/pubmed/id/3092597

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1986-9-26
pubmed:abstractText
Aluminium-containing antacids and sucralfate possess cytoprotective effects supposedly due to the release of endogenous prostaglandins. In the present study possible mechanisms of prostaglandin production by aluminium-containing and related compounds were investigated in cultured macrophages. We found no indication that mechanical action, particle size or hyperosmolality (up to certain limits) play a major role in initiating enhanced prostaglandin production. Instead, it is likely that specific physicochemical properties as surface charge and the corresponding octahedral crystalline structure of Al(OH)3 are major factors mediating the necessary membrane interactions leading to prostaglandin release.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0065-4299
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
375-80
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Release of cytoprotective PGE2 from cultured macrophages induced by antacids and sucralfate.
pubmed:publicationType
Journal Article