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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1986-10-21
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pubmed:abstractText |
Serum samples collected from 69 patients with multiple sclerosis (MS) living in the Hautes-Pyrénées county were tested for immunoglobulin Gm gamma 1, gamma 2, and gamma 3, heavy chain allotypes (Gm system), and immunoglobulin light chain Kappa (Km system). A control group was made up of normal individuals living in the same county. We found a significant excess of individuals with Gm3; +/- 23;5/Gm3; +/- 23;5 amongst the MS patients as compared with controls (relative risk = 2.4). A slight increase of the Km (1) frequency was found in MS patients compared with controls, 21.7% vs 11.8%, but this difference was not significant.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-510X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3091773-France,
pubmed-meshheading:3091773-Gene Frequency,
pubmed-meshheading:3091773-Genetic Markers,
pubmed-meshheading:3091773-Genotype,
pubmed-meshheading:3091773-Humans,
pubmed-meshheading:3091773-Immunoglobulin Allotypes,
pubmed-meshheading:3091773-Immunoglobulin G,
pubmed-meshheading:3091773-Immunoglobulin Light Chains,
pubmed-meshheading:3091773-Multiple Sclerosis,
pubmed-meshheading:3091773-Risk
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pubmed:year |
1986
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pubmed:articleTitle |
Immunoglobulin allotypes and susceptibility to multiple sclerosis. An epidemiological and genetic study in the Hautes-Pyrénées county of France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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