Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1986-9-17
|
pubmed:abstractText |
The effect of long-term TRH administration through drinking water (0.2 mg/ml) on food and water intake and body weight has been studied in three groups of female rats: (1) thyroidectomized, (2) thyroidectomized receiving daily 250 micrograms/kg of L-T4, (3) sham-operated. Treatment with oral TRH for 30 days decreased body weight and increased food intake in sham-operated rats. No TRH effects on body weight or food consumption were observed in either of the other groups of thyroidectomized rats. TRH administration increased circulating T3 levels in sham-operated animals, but had no effects in either hypo- or hyperthyroid, thyroidectomized rats. It can be concluded that the TRH-induced increase on food intake is mediated through the pituitary-thyroid axis.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0091-3057
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1817-9
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3090567-Animals,
pubmed-meshheading:3090567-Body Weight,
pubmed-meshheading:3090567-Drinking,
pubmed-meshheading:3090567-Eating,
pubmed-meshheading:3090567-Female,
pubmed-meshheading:3090567-Hyperthyroidism,
pubmed-meshheading:3090567-Hypothyroidism,
pubmed-meshheading:3090567-Rats,
pubmed-meshheading:3090567-Rats, Inbred Strains,
pubmed-meshheading:3090567-Thyrotropin-Releasing Hormone,
pubmed-meshheading:3090567-Thyroxine,
pubmed-meshheading:3090567-Triiodothyronine
|
pubmed:year |
1986
|
pubmed:articleTitle |
Long-term effects of TRH administration on food intake and body weight in the rat.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|