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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1986-8-11
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pubmed:abstractText |
In this prospective randomized study the effect of oral Ftorafur was compared with that of intravenous 5-fluorouracil in patients with advanced adenocarcinoma of the stomach, colon or rectum. Forty-five patients were evaluable. The overall response rates were 26.9% in the 5-fluorouracil group, 26.7% in the Ftorafur group. The median duration of response was 6 months in both groups. Survival in the 5-fluorouracil group was slightly better than in the Ftorafur group, but the difference was not statistically significant. The myelosuppressive effect of 5-fluorouracil was significantly stronger than that of Ftorafur. Gastrointestinal side effects were more pronounced in the Ftorafur group, but the difference was not statistically significant.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0030-2414
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
212-5
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3088506-Actuarial Analysis,
pubmed-meshheading:3088506-Adenocarcinoma,
pubmed-meshheading:3088506-Aged,
pubmed-meshheading:3088506-Colonic Neoplasms,
pubmed-meshheading:3088506-Female,
pubmed-meshheading:3088506-Fluorouracil,
pubmed-meshheading:3088506-Humans,
pubmed-meshheading:3088506-Male,
pubmed-meshheading:3088506-Middle Aged,
pubmed-meshheading:3088506-Prospective Studies,
pubmed-meshheading:3088506-Random Allocation,
pubmed-meshheading:3088506-Rectal Neoplasms,
pubmed-meshheading:3088506-Stomach Neoplasms,
pubmed-meshheading:3088506-Tegafur
|
pubmed:year |
1986
|
pubmed:articleTitle |
Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|