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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1978-11-18
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pubmed:abstractText |
The activity of rabbit antisera against nu/nu BALB/c lymphocytes was estimated in vivo and in vitro. It was found that anti-lymphocyte serum (ALS) against nu/nu lymph node cells suppressed the alloantigen reaction and the spontaneous rosette-forming cell (sRFC) or plaque-forming cell (PFC) formation for T-dependent (sheep red blood cells) and T-independent (lipopolysaccharide) antigens. ALS against nu/nu spleen cells affected only the sRFC and PFC for T-independent antigen. The former serum exhibited a high cytotoxicity for the suspensions enriched or depleted in B cells, while the latter was more cytotoxic for the suspension enriched in B cells. This may indicate that ALS anti-nu/nu spleen cells is specific for B lymphocytes, and ALS anti nu/nu lymph node cells is directed not only to B cells but also to a subpopulation of T lymphocytes. It may suggest the existence of a subpopulation of T lymphocytes in nu/nu lymph node cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0014-2980
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
531-4
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:308458-Animals,
pubmed-meshheading:308458-Antibody-Producing Cells,
pubmed-meshheading:308458-Antilymphocyte Serum,
pubmed-meshheading:308458-Erythrocytes,
pubmed-meshheading:308458-Graft Survival,
pubmed-meshheading:308458-Lymph Nodes,
pubmed-meshheading:308458-Lymphocytes,
pubmed-meshheading:308458-Mice,
pubmed-meshheading:308458-Mice, Inbred BALB C,
pubmed-meshheading:308458-Mice, Inbred C3H,
pubmed-meshheading:308458-Mice, Nude,
pubmed-meshheading:308458-Rabbits,
pubmed-meshheading:308458-Rosette Formation,
pubmed-meshheading:308458-Sheep,
pubmed-meshheading:308458-T-Lymphocytes
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pubmed:year |
1978
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pubmed:articleTitle |
Properties of antisera against lymphocytes of nude mice.
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pubmed:publicationType |
Journal Article
|