Linked Life Data

3082987

Source:http://linkedlifedata.com/resource/pubmed/id/3082987

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1986-5-22
pubmed:abstractText
The rabbit kappa 2 light chain subtype was described after isolation of the Basilea mutant strain, which does not express the kappa 1 subtype; antibodies raised in domestic rabbits against the Basilea kappa 2 chain recognized antigenic determinants present in Basilea strain rabbits and in some wild Oryctolagus cuniculus individuals. Some authors have proposed that the kappa 2 isotype is expressed in some individuals and is silent in others. The results presented here provide immunochemical and genetic evidence that the kappa 2 isotype presents at least two allotypic forms, bas 1 (equivalent to bas+) and bas 2 (equivalent to the so-called bas-), which are expressed in low levels in all members of the rabbit species. In addition, preliminary data on the expression of the bas 2 allotype in some hares (Lepus capensis) are reported. On the basis of these results, the rules guiding the selection of kappa 1 and kappa 2 isotypic light chain expression in this species may now be approached.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-1767
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
136
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3360-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Allotypy of the rabbit kappa 2 light chain: evidence that the kappa 2 isotype is expressed by all members of the rabbit species.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't