Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-5-14
pubmed:abstractText
Body protein content (as measured by N balance) is normally regulated at a constant level, but is influenced by the level of both energy and N intake. Energy and N act synergistically on N balance. Not all forms of energy are equally effective in maintaining zero N balance; approximately 500 kcal of carbohydrate are required daily by the brain, and this minimum amount of dietary carbohydrate cannot be replaced by fat without loss of body N. Acute illness is accompanied by a catabolic state and an increase in the minimum N intake required for zero N balance. Nutritional depletion induces a metabolic state similar to that typical of growing organisms, in that N can be retained at zero energy balance. BMR includes essential thermogenesis and facultative thermogenesis. In addition, food has a specific dynamic action; it increases metabolic rate. Nutrient-induced increases in metabolic rate are exaggerated in acutely ill patients, such that large amounts of IV glucose may constitute a metabolic stress when given to patients. Equivalent N sparing can be obtained when as much as half of the glucose calories are replaced by fat calories. N balance is an incomplete index of nutritional status, and important information may be gained from measurements of body composition of acutely ill patients; in particular, the degree of expansion of ECW may predict outcome.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0272-5231
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-17
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
The effects of varying energy and nitrogen intake on nitrogen balance, body composition, and metabolic rate.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review