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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1986-4-16
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pubmed:abstractText |
A procedure for the preparation of rat liver microsomal fractions essentially devoid of contaminating lysosomes is described. When this preparation was examined by immunoblotting with a rabbit antiserum to rat 3-hydroxy-3-methylglutaryl-CoA reductase, a single band corresponding to an Mr of 100000 was observed. No evidence was found for glycosylation of rat liver-3-hydroxy-3-methylglutaryl-CoA reductase. Native rat liver microsomal 3-hydroxy-3-methylglutaryl-CoA reductase differs from the purified proteolytically modified species in that it displays allosteric kinetics towards NADPH.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-3850089,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-4111967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-4138239,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-4370710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-4689083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-507825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6088070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6092382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6105157,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6190175,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6389548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6546784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6572913,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6688077,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6693400,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6712656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6863245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6863296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6951166,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-6961444,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-7030342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3082322-728424
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0264-6021
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
233
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
167-72
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3082322-Acetylglucosaminidase,
pubmed-meshheading:3082322-Animals,
pubmed-meshheading:3082322-Cell Fractionation,
pubmed-meshheading:3082322-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:3082322-Hydroxymethylglutaryl CoA Reductases,
pubmed-meshheading:3082322-Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent,
pubmed-meshheading:3082322-Immunoelectrophoresis,
pubmed-meshheading:3082322-Kinetics,
pubmed-meshheading:3082322-Lysosomes,
pubmed-meshheading:3082322-Male,
pubmed-meshheading:3082322-Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase,
pubmed-meshheading:3082322-Microsomes, Liver,
pubmed-meshheading:3082322-NADP,
pubmed-meshheading:3082322-Rats,
pubmed-meshheading:3082322-Rats, Inbred Strains
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pubmed:year |
1986
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pubmed:articleTitle |
Characteristics of rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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