Linked Life Data

3082291

Source:http://linkedlifedata.com/resource/pubmed/id/3082291

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Pt 1
pubmed:dateCreated
1986-4-7
pubmed:abstractText
The combined effects of X-ray irradiation and 5-FU derivatives (5-FU, tegafur, HCFU) treatment were investigated in mouse adenocarcinoma-755. Mice were given a single irradiation 5 Gy or 10 Gy of 6-MV X-rays and orally administered 5-FU derivatives at the time of pre- or post-irradiation. Under these conditions, antitumor activity and survival time were compared between pre- and post-irradiation. Under these conditions, antitumor activity and survival time were compared between pre- and post-irradiation, in combination with 5-FU, tegafur or HCFU. The antitumor effects and survival time were greater for pre-irradiation treatment than for post-irradiation. Among 5-FU derivatives, the highest combination effect was shown by HCFU, followed by 5-FU and tegafur. The concentration of 5-FU in the tumor was correlated with the antitumor effect of each drug.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0385-0684
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
570-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
[Combined effects of radiation and 5-FU derivatives].
pubmed:publicationType
Journal Article, English Abstract