Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-4-1
pubmed:abstractText
The genotoxicity and mutagenicity of 11 fungal metabolites structurally related to sterigmatocystin were examined in the hepatocyte primary culture/DNA-repair test and the Salmonella microsome assay. 10 out of the mycotoxins, i.e. dihydrosterigmatocystin, 5-methoxysterigmatocystin, 5-methoxydihydrosterigmatocystin, 5,6-dimethoxysterigmatocystin, 5,6-dimethoxydihydrosterigmatocystin, sterigmatin, O-methylsterigmatocystin and O-acetylsterigmatocystin showed a positive response for DNA repair, suggesting their carcinogenic potency. 5-Methoxysterigmatocystin, 5,6-dimethoxysterigmatocystin demethylsterigmatocystin and O-acetylsterigmatocystin were mutagenic in TA100 of the bacterial mutagenicity assay with liver S9.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0027-5107
pubmed:author
pubmed:issnType
Print
pubmed:volume
173
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Genotoxic effects of a variety of sterigmatocystin-related compounds in the hepatocyte/DNA-repair test and the Salmonella microsome assay.
pubmed:publicationType
Journal Article, Comparative Study