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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1989-8-14
|
pubmed:abstractText |
In this French study with recombinant somatropin, the stimulation of growth in 32 prepubertal (age 10.0 +/- 3.5 years; mean +/- SD) and 19 pubertal (age 14 +/- 1.5 years) GH deficient children was compared; the stimulation of growth was similarly good in the two groups. The height velocity SD scores increased from -2.5 +/- 1.7 and -0.9 +/- 1.5 to 2.2 +/- 1.9 and 1.6 +/- 1.6 in prepubertal and pubertal children, respectively. Expressed as cm/year, these correspond to increases from 3.2 +/- 1.3 cm/year and 4.1 +/- 1.2 cm/year to 8.1 +/- 1.5 cm/year and 8.6 +/- 1.9 cm/year in the prepubertal and pubertal patients, respectively. Safety and tolerance were good and the immunogenicity of Genotonorm was low.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8843
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
347
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
187-90
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pubmed:dateRevised |
2008-2-20
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pubmed:meshHeading |
pubmed-meshheading:3075838-Adolescent,
pubmed-meshheading:3075838-Antibody Formation,
pubmed-meshheading:3075838-Body Height,
pubmed-meshheading:3075838-Child,
pubmed-meshheading:3075838-Female,
pubmed-meshheading:3075838-France,
pubmed-meshheading:3075838-Growth Hormone,
pubmed-meshheading:3075838-Humans,
pubmed-meshheading:3075838-Male,
pubmed-meshheading:3075838-Multicenter Studies as Topic,
pubmed-meshheading:3075838-Recombinant Proteins
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pubmed:year |
1988
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pubmed:articleTitle |
1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial.
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pubmed:affiliation |
French Multicentre Trial Group, Paris, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Multicenter Study
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