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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1989-8-14
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pubmed:abstractText |
A total of 42 patients (22 previously untreated and 20 previously treated) with GH deficiency were included in a Spanish multicentre trial of recombinant somatropin, 0.5 IU/kg/week. In previously untreated patients typical catch-up growth was observed and the height velocity increased from 3.3 +/- 0.6 cm/year to 9.8 +/- 2.4 cm/year during 1 year of therapy. In previously treated children, the height velocity was maintained (7.2 +/- 2.0 cm/year at the start and 7.9 +/- 1.6 cm/year after 1 year). No anti-GH antibodies were detected in previously untreated patients, and they disappeared from previously treated ones. No adverse reactions were reported.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8843
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
347
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
180-3
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pubmed:dateRevised |
2008-2-20
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pubmed:meshHeading |
pubmed-meshheading:3075836-Antibody Formation,
pubmed-meshheading:3075836-Body Height,
pubmed-meshheading:3075836-Child,
pubmed-meshheading:3075836-Female,
pubmed-meshheading:3075836-Growth Hormone,
pubmed-meshheading:3075836-Humans,
pubmed-meshheading:3075836-Male,
pubmed-meshheading:3075836-Multicenter Studies as Topic,
pubmed-meshheading:3075836-Recombinant Proteins,
pubmed-meshheading:3075836-Spain
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pubmed:year |
1988
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pubmed:articleTitle |
Spanish multicentre trial of recombinant somatropin. Spanish Collaborative Group.
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pubmed:affiliation |
Endocrinology Unit, Children's Hospital Vall d'Hebron, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Multicenter Study
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