Linked Life Data

3070721

Source:http://linkedlifedata.com/resource/pubmed/id/3070721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-5-11
pubmed:abstractText
Although the events underlying the expression of rheumatoid factor in patients with rheumatoid arthritis remain unknown, evidence from both human and animal studies has suggested a role for altered or complexed IgG. Similarly, altered or complexed IgG may also participate in initiating and sustaining inflammation in this disease. Potentially relevant differences in the glycosylation and conformation of rheumatoid IgG compared to IgG from healthy individuals have been detected by several investigators. The latter observations have raised new possibilities concerning mechanisms underlying the pathogenesis of rheumatoid arthritis and, in particular, the production of rheumatoid factor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-3847
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
IgG as antigen in human rheumatoid disease.
pubmed:affiliation
Department of Medicine, University of Alabama School of Medicine, University of Alabama at Birmingham 35294.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review