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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1978-7-24
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pubmed:abstractText |
The occurrence of bacterial infections (B.I.) among 181 children with Hodgkin's disease (121 with splenectomy, 60 without splenectomy) was analyzed. Twenty-seven B.I. occurred among 22 children and included 15 episodes of bacteremia-meningitis in 14 children. B.I. occurred in all age groups, but bacteremia-meningitis occurred most commonly in splenectomized children 10 years of age or less. The frequency of B.I. in splenectomized children receiving radiotherapy was 1.4%, compared to 18.3% among those receiving chemotherapy (p less than 0.05); the frequency of B.I. among non-splenectomized children receiving radiotherapy was 2.8%, compared to 23.1% among those receiving chemotherapy (p less than 0.05). There was no difference in the probability of B.I. as a function of splenectomy for the corresponding groups, although all cases of Streptococcus pneumoniae and Hemophilus influenzae bacteremia-meningitis in splenectomized children. Overwhelming postsplenectomy bacteremia infection not related to active disease or treatment occurred in 3/121 (2.5%) children, accounting for only one fatality (0.8%).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1949-58
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:306282-Adolescent,
pubmed-meshheading:306282-Age Factors,
pubmed-meshheading:306282-Agranulocytosis,
pubmed-meshheading:306282-Antineoplastic Agents,
pubmed-meshheading:306282-Bacterial Infections,
pubmed-meshheading:306282-Child,
pubmed-meshheading:306282-Child, Preschool,
pubmed-meshheading:306282-Female,
pubmed-meshheading:306282-Haemophilus Infections,
pubmed-meshheading:306282-Haemophilus influenzae,
pubmed-meshheading:306282-Hodgkin Disease,
pubmed-meshheading:306282-Humans,
pubmed-meshheading:306282-Infant,
pubmed-meshheading:306282-Male,
pubmed-meshheading:306282-Meningitis,
pubmed-meshheading:306282-Pneumococcal Infections,
pubmed-meshheading:306282-Sepsis,
pubmed-meshheading:306282-Splenectomy
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pubmed:year |
1978
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pubmed:articleTitle |
Bacterial infections in pediatric Hodgkin's disease: relationship to radiotherapy, chemotherapy and splenectomy.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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