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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1989-1-24
|
| pubmed:abstractText |
Our study evaluated whether a dose-response relationship exists for theophylline and diaphragmatic contractility within the usual therapeutic range for theophylline. The study, involving 16 patients with mild to moderate chronic obstructive pulmonary disease, was done in a randomized, placebo-controlled, double-blind, crossover fashion. We found no statistically significant effect of theophylline on diaphragmatic contractility at mean theophylline concentrations of 5.13, 12.07, and 18.6 micrograms/ml.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0003-0805
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
138
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1532-4
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3059899-Clinical Trials as Topic,
pubmed-meshheading:3059899-Diaphragm,
pubmed-meshheading:3059899-Dose-Response Relationship, Drug,
pubmed-meshheading:3059899-Double-Blind Method,
pubmed-meshheading:3059899-Humans,
pubmed-meshheading:3059899-Lung Diseases, Obstructive,
pubmed-meshheading:3059899-Muscle Contraction,
pubmed-meshheading:3059899-Placebos,
pubmed-meshheading:3059899-Random Allocation,
pubmed-meshheading:3059899-Theophylline
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Theophylline and diaphragmatic contractility. Investigation of a dose-response relationship.
|
| pubmed:affiliation |
Department of Medicine, Truman Medical Center-West, Kansas City, Missouri.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|