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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1989-1-24
|
| pubmed:abstractText |
A prospective, randomized study of the potential protective effects of corticosteroids administered as pretreatment against contrast material (CM) reactions is reported. Patients (n = 6,763) from multiple institutions received either a single dose of steroids (32 mg of oral methylprednisolone, approximately 2 hours before CM challenge), a double dose (32 mg approximately 12 hours and 2 hours before CM challenge), or placebo. All contrast injections were with ionic media and were given intravenously. The two-dose (but not the one-dose) corticosteroid regimen provided significant protection. The effect on reaction incidences of a number of historical variables is also tabulated.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0020-9996
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23 Suppl 1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
S193-4
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:3058630-Anaphylaxis,
pubmed-meshheading:3058630-Contrast Media,
pubmed-meshheading:3058630-Humans,
pubmed-meshheading:3058630-Methylprednisolone,
pubmed-meshheading:3058630-Multicenter Studies as Topic,
pubmed-meshheading:3058630-Premedication,
pubmed-meshheading:3058630-Prospective Studies,
pubmed-meshheading:3058630-Random Allocation
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Protective effects of corticosteroids in contrast material anaphylaxis.
|
| pubmed:affiliation |
Department of Radiology, UCSD School of Medicine, La Jolla 92093-0632.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Multicenter Study
|