Linked Life Data

3058492

Source:http://linkedlifedata.com/resource/pubmed/id/3058492

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
1989-1-26
pubmed:abstractText
Three potential predictors (i.e., biomarkers) of longevity in mammals are proposed: (1) age of pubertal onset, (2) concentrations of gonadal steroids and (3) timing of age-related infertility. Ages of pubertal onset and of declining fertility are hypothesized to be positively correlated with longevity. Concentrations of and androgens and estrogens are proposed to be inversely and positively correlated, respectively, with life span. Evidence upon which these hypotheses are based is reviewed and its limitations are discussed. General strategies for testing these hypotheses are outlined. In addition, several pragmatic as well as theoretical issues facing research on biomarkers of aging are discussed, using specific examples derived from studies of female reproductive aging.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0531-5565
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-67
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Puberty, gonadal steroids and fertility: potential reproductive markers of aging.
pubmed:affiliation
Department of Obstetrics and Gynecology, McGill University, Royal Victoria Hospital, Montreal, Quebec, Canada.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't