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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1989-1-10
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pubmed:abstractText |
The authors studied 46 patients with the operationally defined syndrome of postpsychotic depression following episodes of schizophrenia or schizoaffective disorder. Half of these patients were also found to satisfy criteria for negative symptoms. The patients with negative symptoms were rated as more severely ill on global measures, but there was only limited evidence that they were more depressed. Nevertheless, in a randomized double-blind trial of imipramine versus placebo as an adjunct to the fluphenazine decanoate and benztropine regimens of the patients with negative symptoms, the patients who received imipramine seemed to show more improvement.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-953X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1532-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3057924-Adolescent,
pubmed-meshheading:3057924-Adult,
pubmed-meshheading:3057924-Aged,
pubmed-meshheading:3057924-Benztropine,
pubmed-meshheading:3057924-Clinical Trials as Topic,
pubmed-meshheading:3057924-Depressive Disorder,
pubmed-meshheading:3057924-Double-Blind Method,
pubmed-meshheading:3057924-Drug Therapy, Combination,
pubmed-meshheading:3057924-Female,
pubmed-meshheading:3057924-Fluphenazine,
pubmed-meshheading:3057924-Humans,
pubmed-meshheading:3057924-Imipramine,
pubmed-meshheading:3057924-Male,
pubmed-meshheading:3057924-Middle Aged,
pubmed-meshheading:3057924-Psychiatric Status Rating Scales,
pubmed-meshheading:3057924-Psychotic Disorders,
pubmed-meshheading:3057924-Random Allocation,
pubmed-meshheading:3057924-Schizophrenia,
pubmed-meshheading:3057924-Schizophrenic Psychology
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pubmed:year |
1988
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pubmed:articleTitle |
Postpsychotic depression and negative symptoms: an investigation of syndromal overlap.
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pubmed:affiliation |
Mount Sinai School of Medicine, City University of New York.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
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