Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1989-1-6
pubmed:abstractText
We report on a case of leiomyosarcoma of the thyroid with ultrastructural features and expression of intermediate filament proteins different from that of anaplastic carcinomas. Histologic examination of multiple sections showed that they were leiomyosarcomatous, and neither epithelial features nor giant cell configurations were found. Electron microscopic examination showed microfilament bundles with dense patches and discontinuous basal lamina. Desmin, vimentin, and actin were positive for tumor cells, and cytokeratin, thyroglobulin, and calcitonin were negative. In contrast, the anaplastic carcinoma cases did not contain microfilament bundles with dense patches in their tumor cells. There were no desmin-positive or cytokeratin-negative tumor cells. We concluded that this case was a primary leiomyosarcoma, presumably derived from the smooth muscle cell of the vascular wall.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2558-63
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Leiomyosarcoma of the thyroid gland. A case report with a comparative study of five cases of anaplastic carcinoma.
pubmed:affiliation
Department of Pathology, School of Medicine, Kanazawa University, Japan.
pubmed:publicationType
Journal Article, Comparative Study, Review, Case Reports