Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1988-12-22
|
pubmed:abstractText |
A randomized clinical study of adjuvant immunotherapy with decaris was carried out in patients with early breast cancer. 92 patients with stages I and IIA tumors (T1,2N0M0) received 300 mg decaris weekly (150 mg for 2 successive days) 2 weeks after radical mastectomy (Patey) used as a sole preventive therapy. The short (1 month) (group I), the medium (3 months) (group 2) and the long-term intermittent (three 3 month courses during 15 months) (group 3) modalities were compared. The prolonged intermittent course of decaris administration proved superior since it assured improvement in immunity and longer relapse-free survival, and lacked apparent toxicity. Five-year survival in all decaris treated patients was 93.8%, while five-year relapse-free course in group 3 was registered in 96.9%.
|
pubmed:language |
rus
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0507-3758
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
34
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1182-8
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3055672-Adult,
pubmed-meshheading:3055672-Breast Neoplasms,
pubmed-meshheading:3055672-Clinical Trials as Topic,
pubmed-meshheading:3055672-Female,
pubmed-meshheading:3055672-Humans,
pubmed-meshheading:3055672-Immunoglobulin G,
pubmed-meshheading:3055672-Immunoglobulin M,
pubmed-meshheading:3055672-Levamisole,
pubmed-meshheading:3055672-Middle Aged,
pubmed-meshheading:3055672-Random Allocation,
pubmed-meshheading:3055672-Rosette Formation,
pubmed-meshheading:3055672-T-Lymphocytes,
pubmed-meshheading:3055672-Time Factors
|
pubmed:year |
1988
|
pubmed:articleTitle |
[Immunotherapy with decaris in the early stages of breast cancer].
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Randomized Controlled Trial
|