Linked Life Data

3052976

Source:http://linkedlifedata.com/resource/pubmed/id/3052976

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
236
pubmed:dateCreated
1988-12-2
pubmed:abstractText
This study examined the efficacy of heparinized biodegradable materials in the prevention of post-laminectomy scar formation using a canine system. Six-level noncontiguous laminectomies were performed on five adult canines. Exposed dura at each level was covered with the following: (1) nothing (control); (2) fat; (3) fat and autogeneic bone; (4) heparinized Avitene; (5) heparinized Surgicel; or (6) heparinized collagen gel. Canines were killed 16 weeks postoperatively and histologic specimens examined. Fibrous adhesions were abundant at Site 1 (control). Free fat grafts were well preserved and did not permit adhesions at Sites 2 and 3. None of the heparinized materials was as effective as fat in controlling scar formation. Overlying bone at Site 3 did not alter the quality of a free fat graft placed over the dura, a point possibly significant for laminectomies followed by fusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0009-921X
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
166-74
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Heparinized materials for control of the formation of the laminectomy membrane in experimental laminectomies in dogs.
pubmed:affiliation
Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Ohio.
pubmed:publicationType
Journal Article, Comparative Study