| pubmed-article:30506 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C0007450 | lld:lifeskim |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C0028058 | lld:lifeskim |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C0025562 | lld:lifeskim |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C0040373 | lld:lifeskim |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:30506 | lifeskim:mentions | umls-concept:C1705242 | lld:lifeskim |
| pubmed-article:30506 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:30506 | pubmed:dateCreated | 1979-1-26 | lld:pubmed |
| pubmed-article:30506 | pubmed:abstractText | The alpha-adrenoceptor blocking agent, tolazoline, and the O-methylated metabolite of adrenaline, metanephrine, produced a concentration-dependent increase of tension in the smooth muscle of the cat isolated nictitating membrane. These effects were considered to be due to the activation of postsynaptic alpha-adrenoceptors. 2 The responses to nerve stimulation of this muscle were neither potentiated nor blocked by tolazoline (0.1 to 10 micrometer) or metanephrine (1 to 10 micrometer). 3 3H-transmitter overflow evoked by electrical stimulation was not modified by tolazoline or metanephrine in concentrations in which these drugs stimulated the postsynaptic alpha-adrenoceptors. 4 Since tolazoline and metanephrine failed to activate the presynaptic alpha-adrenoceptors of the cat nictitating membrane under experimental conditions in which they stimulated the postsynaptic alpha-adrenoceptors, these results further support the view that the presynaptic (alpha2) adrenoceptors differ from the postsynaptic (alpha1) adrenoceptors. | lld:pubmed |
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| pubmed-article:30506 | pubmed:language | eng | lld:pubmed |
| pubmed-article:30506 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:30506 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:30506 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:30506 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:30506 | pubmed:issn | 0007-1188 | lld:pubmed |
| pubmed-article:30506 | pubmed:author | pubmed-author:LangerS ZSZ | lld:pubmed |
| pubmed-article:30506 | pubmed:author | pubmed-author:ArbillaSS | lld:pubmed |
| pubmed-article:30506 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:30506 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:30506 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:30506 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:30506 | pubmed:pagination | 259-64 | lld:pubmed |
| pubmed-article:30506 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:30506 | pubmed:year | 1978 | lld:pubmed |
| pubmed-article:30506 | pubmed:articleTitle | Differences between presynaptic and postsynaptic alpha-adrenoceptors in the isolated nictitating membrane of the cat: effects of metanephrine and tolazoline. | lld:pubmed |
| pubmed-article:30506 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:30506 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:30506 | pubmed:publicationType | In Vitro | lld:pubmed |
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