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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1988-11-17
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pubmed:abstractText |
An anti-Klebsiella pneumoniae K5a capsular polysaccharide vaccine was evaluated as a preventive approach for protecting squirrel monkeys, Saimiri sciureus, in our breeding colony. Based on an 8-month vaccination schedule over a period of more than two years, this vaccine, regardless of the animal's age, resulted in a reduction of this particular bacterial infection and its generally associated fatal outcome. IgG antibody responses in naive and vaccinated animals were monitored over an extended period by radioimmunoassay and showed a marked increase above the initial naturally occurring antibody titres. No side-effects were observed after repeated vaccination of several hundred animals during a two-year period.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0769-2625
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
139
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
401-7
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pubmed:dateRevised |
2007-7-24
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pubmed:meshHeading |
pubmed-meshheading:3048318-Animals,
pubmed-meshheading:3048318-Bacterial Vaccines,
pubmed-meshheading:3048318-Female,
pubmed-meshheading:3048318-Klebsiella Infections,
pubmed-meshheading:3048318-Klebsiella pneumoniae,
pubmed-meshheading:3048318-Male,
pubmed-meshheading:3048318-Polysaccharides, Bacterial,
pubmed-meshheading:3048318-Saimiri,
pubmed-meshheading:3048318-Vaccination
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pubmed:articleTitle |
Protection against fatal Klebsiella pneumoniae sepsis in the squirrel monkey Saimiri sciureus after immunization with a capsular polysaccharide vaccine.
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pubmed:affiliation |
Laboratoire d'Immunologie Parasitaire, Institut Pasteur, Cayenne, Guyane Française.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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