Linked Life Data

3045846

Source:http://linkedlifedata.com/resource/pubmed/id/3045846

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-10-11
pubmed:abstractText
Bilateral injection of procaine into the VMH resulted in a decrease in serum glucose and immunoreactive insulin levels in both food-deprived rats and meal-fed rats. Corticosterone levels and gastric emptying rate were unaffected by these VMH procaine injections. Since it is likely that the procaine disrupted only those neurons whose cell bodies and synapses lay in the region of the VMH, the results suggest that the two major factors in the etiology of the 'VMH syndrome' following electrolytic lesions, rapid emptying and insulin hyperresponsivity, are dependent upon destruction of fibers of passage through the VMH. Finally, the results further support the proposal that the VMH exerts tonic excitatory control over liver glucose output.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-33
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Effect of procaine injection into the ventromedial hypothalamic area (VMH) of the rat on serum insulin, glucose and corticosterone and gastric emptying rate.
pubmed:affiliation
Garvan Institute of Medical Research, St. Vincent's Hospital Darlinghurst, N.S.W. Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't