Linked Life Data

3044159

Source:http://linkedlifedata.com/resource/pubmed/id/3044159

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-9-16
pubmed:abstractText
Autoregulation of cerebral blood flow is an essential homeostatic mechanism which is easily disturbed during the stresses in the birth process. In its absence, moderate hypotension, a frequent complication in neonatal asphyxia, may induce cerebral ischemia, the arterial watershed zones in periventricular regions being particularly prone. The initial ischemia in perinatal stress produces functional disturbance (EEG depression), which is not readily reversible as the circulation improves. Hypotension, cerebral hypoperfusion and EEG depression precedes severe periventricular hemorrhage, which seems to be triggered by fluctuations in arterial blood pressure and flow, with fluctuations in the transmural pressure gradient across the capillary wall. The penetration of the hemorrhaging into surrounding brain tissue is related to the magnitude of the preceding ischemic insult.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0387-7604
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
143-6
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
The "lost autoregulation hypothesis" and brain lesions in the newborn--an update.
pubmed:affiliation
John F Kennedy Institute, Glostrup, Denmark.
pubmed:publicationType
Journal Article, Review