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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1988-9-21
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pubmed:abstractText |
The use of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) following autologous marrow transplantation for lymphoid malignancies was explored in a phase I/II dose escalation study. rhGM-CSF given as a 2-hour infusion daily for 14 days was well tolerated at doses up to 240 micrograms/m2/day. When compared with 86 disease-matched and treatment-matched historical controls, patients receiving greater than or equal to 60 micrograms/m2/day rhGM-CSF recovered neutrophil and platelet counts more rapidly, had fewer days with fever, and were discharged from the hospital sooner.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-4971
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
834-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3042050-Blood Platelets,
pubmed-meshheading:3042050-Bone Marrow Transplantation,
pubmed-meshheading:3042050-Colony-Stimulating Factors,
pubmed-meshheading:3042050-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:3042050-Growth Substances,
pubmed-meshheading:3042050-Humans,
pubmed-meshheading:3042050-Leukemia,
pubmed-meshheading:3042050-Lymphoma,
pubmed-meshheading:3042050-Recombinant Proteins,
pubmed-meshheading:3042050-Transplantation, Autologous
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pubmed:year |
1988
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pubmed:articleTitle |
Use of recombinant human granulocyte-macrophage colony-stimulating factor in autologous marrow transplantation for lymphoid malignancies.
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pubmed:affiliation |
Fred Hutchinson Cancer Research Center, Seattle, WA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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