Linked Life Data

3039303

Source:http://linkedlifedata.com/resource/pubmed/id/3039303

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1987-9-24
pubmed:abstractText
The regulation of sacB, the gene encoding Bacillus subtilis levansucrase is altered by mutations located in several loci unlinked to sacB. Amongst these, the sacS locus seems to play an important role in the induction of sacB by sucrose. We have cloned sacS and found evidence suggesting that it contains two genes. The product of the first gene might repress the expression of the second; the second gene encodes a positive regulator of levansucrase synthesis, since its deletion abolishes this synthesis. There is a palindromic sequence resembling Q-independent terminators between the sacB promoter and the structural gene. Mutations affecting this palindrome make sacB constitutive. This suggests that the putative terminator is involved in the induction of sacB by sucrose. We discuss the possibility that the sacS-encoded positive regulator is a sucrose-dependent antiterminator which modulates transcription termination between the sacB promoter and the structural gene.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0026-8925
pubmed:author
pubmed:issnType
Print
pubmed:volume
208
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
114-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Cloning and preliminary characterization of the sacS locus from Bacillus subtilis which controls the regulation of the exoenzyme levansucrase.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't