Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1987-9-14
|
pubmed:abstractText |
In order to evaluate the influence of pregnancy on the presence of human papillomavirus (HPV) in the lower female genital tract, cervical smears of 92 pregnant and 96 non-pregnant women, matched by age, were examined for the presence of HPV-DNA by means of Southern blot hybridization. All patients had negative PAP smears. Twenty-six (28%) of the pregnant women and 12 (12.5%) of the non-pregnant women were positive for HPV. HPV 16 accounted for 42% of all positive pregnant cases and only 25% of the positive non-pregnant cases. Smears of pregnant patients contained more than 10 pg viral DNA in 45% of the cases against 20% in the non-pregnant group. HPV 16 showed the most active replication in both groups. This study demonstrates an increased prevalence of HPV (preferentially of HPV 16) and a higher replication rate of viral DNA during pregnancy.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0020-7136
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
40
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
198-201
|
pubmed:dateRevised |
2007-7-24
|
pubmed:meshHeading |
pubmed-meshheading:3038757-Adult,
pubmed-meshheading:3038757-Cervix Mucus,
pubmed-meshheading:3038757-DNA, Viral,
pubmed-meshheading:3038757-DNA Replication,
pubmed-meshheading:3038757-Female,
pubmed-meshheading:3038757-Humans,
pubmed-meshheading:3038757-Papillomaviridae,
pubmed-meshheading:3038757-Pregnancy,
pubmed-meshheading:3038757-Pregnancy Complications, Infectious,
pubmed-meshheading:3038757-Virus Replication
|
pubmed:year |
1987
|
pubmed:articleTitle |
Increased prevalence of human papillomaviruses in the lower genital tract of pregnant women.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|