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pubmed-article:3037449pubmed:abstractTextThe striatonigral neurokinin A (NKA) pathway in rats was examined with an antiserum specific to the N-terminal region of NKA. Thermal lesions of the striatum decreased both substance P-like immunoreactivity (SP-LI) and NKA-like immunoreactivity (NKA-LI) in the substantia nigra (SN). The releases of SP-LI and NKA-LI in the SN were measured by a push pull superfusion technique. Addition of 50 mM K+ to the superfusion medium increased the releases of both SP-LI and NKA-LI to 1.5-2.0 times the basal values. These results suggest that NKA neurons as well as SP neurons in the striatum project to the SN in rats.lld:pubmed
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pubmed-article:3037449pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:3037449pubmed:year1987lld:pubmed
pubmed-article:3037449pubmed:articleTitleEvidence that neurokinin A (substance K) neurons project from the striatum to the substantia nigra in rats.lld:pubmed
pubmed-article:3037449pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3037449pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed