Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1987-8-10
|
pubmed:abstractText |
The striatonigral neurokinin A (NKA) pathway in rats was examined with an antiserum specific to the N-terminal region of NKA. Thermal lesions of the striatum decreased both substance P-like immunoreactivity (SP-LI) and NKA-like immunoreactivity (NKA-LI) in the substantia nigra (SN). The releases of SP-LI and NKA-LI in the SN were measured by a push pull superfusion technique. Addition of 50 mM K+ to the superfusion medium increased the releases of both SP-LI and NKA-LI to 1.5-2.0 times the basal values. These results suggest that NKA neurons as well as SP neurons in the striatum project to the SN in rats.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0304-3940
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
77
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
103-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3037449-Animals,
pubmed-meshheading:3037449-Corpus Striatum,
pubmed-meshheading:3037449-Male,
pubmed-meshheading:3037449-Neurokinin A,
pubmed-meshheading:3037449-Neurons,
pubmed-meshheading:3037449-Neuropeptides,
pubmed-meshheading:3037449-Rats,
pubmed-meshheading:3037449-Rats, Inbred Strains,
pubmed-meshheading:3037449-Substantia Nigra
|
pubmed:year |
1987
|
pubmed:articleTitle |
Evidence that neurokinin A (substance K) neurons project from the striatum to the substantia nigra in rats.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|