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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
1987-6-9
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pubmed:databankReference |
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pubmed:abstractText |
Biologically active molecular clones of avian sarcoma virus 17 (ASV 17) contain a replication-defective proviral genome of 3.5 kilobases (kb). The genome retains partial gag and env sequences, which flank a cell-derived putative oncogene of 0.93 kb, termed jun. The jun gene lacks preserved coding domains of tyrosine-specific protein kinases. It also shows no significant nucleic acid homology with other known oncogenes. The probable transformation-specific protein in ASV 17-transformed cells is a 55-kDa gag-jun fusion product.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2848-52
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3033666-Amino Acid Sequence,
pubmed-meshheading:3033666-Animals,
pubmed-meshheading:3033666-Avian Sarcoma Viruses,
pubmed-meshheading:3033666-Base Sequence,
pubmed-meshheading:3033666-Cell Transformation, Neoplastic,
pubmed-meshheading:3033666-Cells, Cultured,
pubmed-meshheading:3033666-Chick Embryo,
pubmed-meshheading:3033666-DNA Restriction Enzymes,
pubmed-meshheading:3033666-Genes, Viral,
pubmed-meshheading:3033666-Nucleic Acid Hybridization,
pubmed-meshheading:3033666-Oncogene Proteins, Viral,
pubmed-meshheading:3033666-Oncogenes,
pubmed-meshheading:3033666-Transfection
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pubmed:year |
1987
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pubmed:articleTitle |
Avian sarcoma virus 17 carries the jun oncogene.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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