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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1987-6-15
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pubmed:abstractText |
We have recorded NOESY spectra of two non-selfcomplementary undecanucleotide duplexes. From the observed NOEs we do not detect any significant distortion of the helix when a G-C pair is replaced by a G-T pair and the normal interresidue connectivities can be followed through the mismatch site. We conclude that the 2D spectra of the non-exchangeable protons do not allow differentiation between a wobble or rare tautomer form for the mismatch. NOE measurements in H2O, however, clearly show that the mismatch adopts a wobble structure and give information on the hydration in the minor groove for the G-T base pair which is embedded between two A-T base pairs in the sequence.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-13063483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-16593539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-2951250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-3783714,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-3801424,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-4063337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-4093986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-5969078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6225697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6301539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6308634,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6317867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6370613,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6397313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6397316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6504700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6652060,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6661418,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6698006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-6722097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-673842,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-7066295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-7338904,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3033602-958483
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0305-1048
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3397-409
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pubmed:dateRevised |
2010-9-9
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pubmed:meshHeading |
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pubmed:year |
1987
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pubmed:articleTitle |
Comparison of the conformation of an oligonucleotide containing a central G-T base pair with the non-mismatch sequence by proton NMR.
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pubmed:publicationType |
Journal Article,
Comparative Study
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