Linked Life Data

3031854

Source:http://linkedlifedata.com/resource/pubmed/id/3031854

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-5-20
pubmed:abstractText
Mice given 10-weekly injections (i.m.) of 20 mumol of isopropyl methanesulfonate (IPMS) in trioctanoin exhibited depressed hematopoiesis as manifested by reduced peripheral blood counts and by reduced thymic and bone marrow cellularities. The treatments were particularly toxic to erythroid populations and ultimately induced signs of splenic erythropoiesis. Bone marrow cellularity recovered during the latter stages of the treatments indicating that subpopulations of hematopoietic cells were resistant to the treatments. This recovery of bone marrow cellularity may bear on the recently discovered leukemogenic potential of IPMS.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0378-4274
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Isopropyl methanesulfonate is a potent red cell hematotoxicant.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't