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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1977-11-25
|
| pubmed:abstractText |
Human macrophages procured by culture of adherent peripheral blood mononuclear cells were investigated for reactivity in complement-dependent cytotoxicity tests with antisera having specificity for HLA-D-associated 'Ia-like' B-cell antigens. The antisera were found to be cytotoxic for 30%-70% of the macrophages from donors whose B cells were also reactive, and absorption with B cells also removed macrophage cytotoxicity. A B-cell xenoantiserum was also cytotoxic to macrophages. It is concluded that the HLA-D-associated 'Ia-like' antigens present on B cells are also expressed by macrophages, at least on a subpopulation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0300-9475
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
907-12
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:302981-B-Lymphocytes,
pubmed-meshheading:302981-Cells, Cultured,
pubmed-meshheading:302981-Complement Fixation Tests,
pubmed-meshheading:302981-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:302981-HLA Antigens,
pubmed-meshheading:302981-Histocompatibility Testing,
pubmed-meshheading:302981-Humans,
pubmed-meshheading:302981-Immune Sera,
pubmed-meshheading:302981-Macrophages
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
HLA-D-associated 'Ia-like' antigens on human macrophages.
|
| pubmed:publicationType |
Journal Article
|