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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1987-2-24
|
| pubmed:abstractText |
Twelve adults with hepatocellular carcinoma (HCC) and 8 individuals with histologically normal liver, were measured for serum selenium concentration and glutathione peroxidase (GSH-Px) of liver tissue. It was found a reduced serum selenium and liver GSH-Px in patients with HCC. Serum selenium concentration and the enzyme activity were positively correlated (p less than 0.01). The increased risk of carcinoma in selenium deficiency may be partially due to a reduced activity of GSH-Px, one of the most important scavenger enzymes of oxygen toxic radicals.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0300-8916
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
31
|
| pubmed:volume |
72
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
617-9
|
| pubmed:dateRevised |
2008-12-12
|
| pubmed:meshHeading |
pubmed-meshheading:3027933-Carcinoma, Hepatocellular,
pubmed-meshheading:3027933-Female,
pubmed-meshheading:3027933-Glutathione Peroxidase,
pubmed-meshheading:3027933-Humans,
pubmed-meshheading:3027933-Liver,
pubmed-meshheading:3027933-Liver Neoplasms,
pubmed-meshheading:3027933-Male,
pubmed-meshheading:3027933-Selenium
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
Reduction of liver glutathione peroxidase activity and deficiency of serum selenium in patients with hepatocellular carcinoma.
|
| pubmed:publicationType |
Journal Article
|