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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7000
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pubmed:dateCreated |
1987-2-25
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pubmed:abstractText |
The genes encoding the alpha and beta chains of the T-cell receptor (Ti) of an antigen-specific, Ia-restricted murine T-cell hybridoma were introduced into T3-positive or T3-negative human T cells. The resultant transfectants express either mouse-human or mouse-mouse Ti alpha beta molecules functionally associated with the human T3 complex. Only the complete murine Ti alpha beta dimer mediates specific functional corecognition of the appropriate antigen-Ia pair.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0028-0836
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
325
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
125-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3027582-Animals,
pubmed-meshheading:3027582-Cell Membrane,
pubmed-meshheading:3027582-Cytochrome c Group,
pubmed-meshheading:3027582-Endocytosis,
pubmed-meshheading:3027582-Histocompatibility Antigens Class II,
pubmed-meshheading:3027582-Humans,
pubmed-meshheading:3027582-Interleukin-2,
pubmed-meshheading:3027582-Macromolecular Substances,
pubmed-meshheading:3027582-Mice,
pubmed-meshheading:3027582-RNA, Messenger,
pubmed-meshheading:3027582-Receptors, Antigen, T-Cell,
pubmed-meshheading:3027582-Species Specificity,
pubmed-meshheading:3027582-T-Lymphocytes,
pubmed-meshheading:3027582-Transcription, Genetic,
pubmed-meshheading:3027582-Transfection
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pubmed:articleTitle |
Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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