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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-2-25
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pubmed:abstractText |
An infectious center viral plaque assay has been utilized to quantitate activated T suppressor (Ts) cells. This assay is based on two observations. Namely, resting T cells do not serve as good replicative hosts for many viruses, including vesicular stomatitis virus (VSV), and that Ts cells can be enriched by their ability to bind to antigen-coated dishes. Our data show that Ts cells specific for either the TNP hapten or for dextran will replicate VSV upon antigenic and/or mitogenic activation, whereas resting Ts and hapten-specific B cells are less efficient in this process. This system will now allow the direct quantitation of Ts cells and their activation properties.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-8749
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
190-4
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3026659-Animals,
pubmed-meshheading:3026659-Antigens,
pubmed-meshheading:3026659-Cell Transformation, Viral,
pubmed-meshheading:3026659-Lymphocyte Activation,
pubmed-meshheading:3026659-Lymphokines,
pubmed-meshheading:3026659-Male,
pubmed-meshheading:3026659-Mice,
pubmed-meshheading:3026659-Mice, Inbred BALB C,
pubmed-meshheading:3026659-Mice, Inbred C57BL,
pubmed-meshheading:3026659-T-Lymphocytes, Regulatory,
pubmed-meshheading:3026659-Vesicular stomatitis Indiana virus,
pubmed-meshheading:3026659-Virus Replication
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pubmed:year |
1987
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pubmed:articleTitle |
VSV replication in normal and transformed T cells, an assay for T suppressor cell activation.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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