pubmed-article:3022937 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3022937 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:3022937 | lifeskim:mentions | umls-concept:C0254837 | lld:lifeskim |
pubmed-article:3022937 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:3022937 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
pubmed-article:3022937 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:3022937 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:3022937 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:3022937 | pubmed:dateCreated | 1986-12-30 | lld:pubmed |
pubmed-article:3022937 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3022937 | pubmed:abstractText | The nucleotide sequence for the human nerve growth factor (NGF) receptor has been determined. The 3.8 kb receptor mRNA encodes a 427 amino acid protein containing a 28 amino acid signal peptide, an extracellular domain containing four 40 amino acid repeats with six cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155 amino acid cytoplasmic domain. The sequence of the extracellular domain of the NGF receptor predicts a highly ordered structure containing a negatively charged region that may serve as the ligand-binding site. This domain is conserved through evolution. Transfection of a full-length cDNA in mouse fibroblasts results in stable expression of NGF receptors that are recognized by monoclonal antibodies to the human NGF receptor and that bind [125I]NGF. | lld:pubmed |
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pubmed-article:3022937 | pubmed:language | eng | lld:pubmed |
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pubmed-article:3022937 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:3022937 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3022937 | pubmed:month | Nov | lld:pubmed |
pubmed-article:3022937 | pubmed:issn | 0092-8674 | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:JohnsonDD | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:SehgalAA | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:ChanLL | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:MorganCC | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:BuckC RCR | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:MercerEE | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:BothwellMM | lld:pubmed |
pubmed-article:3022937 | pubmed:author | pubmed-author:LanahanAA | lld:pubmed |
pubmed-article:3022937 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3022937 | pubmed:day | 21 | lld:pubmed |
pubmed-article:3022937 | pubmed:volume | 47 | lld:pubmed |
pubmed-article:3022937 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3022937 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3022937 | pubmed:pagination | 545-54 | lld:pubmed |
pubmed-article:3022937 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:3022937 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3022937 | pubmed:articleTitle | Expression and structure of the human NGF receptor. | lld:pubmed |
pubmed-article:3022937 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3022937 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:3022937 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:3022937 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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