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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1986-12-15
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pubmed:abstractText |
In a longitudinal study we examined by immunoblotting (IB) the development and the evolution of the humoral immune response against individual cytomegalovirus (CMV) structural polypeptides in a total of 80 serum samples from 13 renal transplant recipients showing serological evidence of CMV infection and five renal transplant recipients with an anti-CMV antibody level unchanged over the observation period. The results showed that the IB reactivity at the time of transplantation may be a good index of the host's humoral immune status against CMV; by using this procedure it is possible to identify a seroconversion by the detection of antibodies reacting with some intermediate molecular weight proteins in sera examined at high dilution. Furthermore, IB is a very sensitive procedure also for IgM detection as it anticipates the positivity of the enzyme immune assay for IgM.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0385-5600
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
683-95
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3022114-Antibodies, Viral,
pubmed-meshheading:3022114-Antigens, Viral,
pubmed-meshheading:3022114-Cells, Cultured,
pubmed-meshheading:3022114-Complement Fixation Tests,
pubmed-meshheading:3022114-Cytomegalovirus,
pubmed-meshheading:3022114-Embryo, Mammalian,
pubmed-meshheading:3022114-Humans,
pubmed-meshheading:3022114-Immunoenzyme Techniques,
pubmed-meshheading:3022114-Kidney Transplantation,
pubmed-meshheading:3022114-Longitudinal Studies,
pubmed-meshheading:3022114-Reagent Kits, Diagnostic,
pubmed-meshheading:3022114-Viral Proteins
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pubmed:year |
1986
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pubmed:articleTitle |
Serum antibodies to individual cytomegalovirus structural polypeptides in renal transplant recipients during viral infection.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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