Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-12-3
pubmed:abstractText
Two monoclonal antibodies, E8B3 and E8D2, were raised against Epstein-Barr virus (EBV)-producing cells and were shown to immunoprecipitate a protein with an approximate molecular weight of 105,000 (p105). The protein was detectable only in EBV-containing cells which were supporting the virus lytic cycle, and its synthesis increased after cells were induced with phorbol esters. The molecule was radiolabeled and immunoprecipitated from virus-producing cells that had been extrinsically labeled with 125I, and the antibodies E8B3 and E8D2 reacted in immunofluorescence assays with infected cells; the molecule was also associated with virion particles. Synthesis of p105 was not blocked by phosphonoacetic acid and could be induced in Raji cells by superinfection with virus derived from P3HR1 cells. These data support the conclusion that p105 is an EBV-specific early membrane protein.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-14086209, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-202665, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-204874, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-208266, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-224538, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-3001337, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-3838905, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-4365906, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-4567231, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-4850204, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-4912237, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-4916222, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6087149, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6154378, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6168775, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6177865, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6247820, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6261001, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6263973, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6276755, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6289637, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6295961, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6315853, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-6337215, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-637870, http://linkedlifedata.com/resource/pubmed/commentcorrection/3021971-89099
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-538X
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
369-75
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Detection by monoclonal antibodies of an early membrane protein induced by Epstein-Barr virus.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.