| pubmed-article:3018521 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C0079053 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C1704222 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C1881379 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:3018521 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:3018521 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:3018521 | pubmed:dateCreated | 1986-10-3 | lld:pubmed |
| pubmed-article:3018521 | pubmed:abstractText | The McDonough strain of feline sarcoma virus contains an oncogene called v-fms whose ultimate protein product (gp140v-fms) resembles a cell surface growth factor receptor. To identify and characterize the protein product of the proto-oncogene c-fms, antisera were prepared to the viral fms sequences and used to detect specific cross-reacting sequences in human choriocarcinoma cells (BeWo) known to express c-fms mRNA. Both tumor-bearing rat sera and a rabbit antiserum prepared to a segment of v-fms expressed in Escherichia coli detected a 140-kilodalton (kDa) glycoprotein in the BeWo cells. Tryptic fingerprint analysis of [35S]methionine-labeled proteins indicated that the viral fms proteins and the 140-kDa BeWo cell protein were highly related. This 140-kDa glycoprotein contained an associated tyrosine kinase activity in vitro and was labeled principally on serine after 32Pi metabolic labeling. These results suggest that the 140-kDa protein in BeWo cells is the protein product of the human c-fms proto-oncogene. This conclusion is supported by the finding that a similar protein is detectable only in other human cells that express c-fms mRNA. These other human cells include adherent monocytes and the cell line ML-1, which can be induced to differentiate along the monocyte-macrophage pathway. This is in agreement with current thought that the c-fms proto-oncogene product functions as the CSF-1 receptor specific to this pathway. | lld:pubmed |
| pubmed-article:3018521 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3018521 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3018521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3018521 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3018521 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:3018521 | pubmed:issn | 0270-7306 | lld:pubmed |
| pubmed-article:3018521 | pubmed:author | pubmed-author:Rohrschneider... | lld:pubmed |
| pubmed-article:3018521 | pubmed:author | pubmed-author:WoolfordJJ | lld:pubmed |
| pubmed-article:3018521 | pubmed:author | pubmed-author:RothwellVV | lld:pubmed |
| pubmed-article:3018521 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3018521 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:3018521 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3018521 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3018521 | pubmed:pagination | 3458-66 | lld:pubmed |
| pubmed-article:3018521 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:meshHeading | pubmed-meshheading:3018521-... | lld:pubmed |
| pubmed-article:3018521 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:3018521 | pubmed:articleTitle | Characterization of the human c-fms gene product and its expression in cells of the monocyte-macrophage lineage. | lld:pubmed |
| pubmed-article:3018521 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3018521 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3018521 | lld:pubmed |
