|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
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|
pubmed:dateCreated |
1986-10-1
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|
pubmed:abstractText |
Twenty-five children with acquired immune deficiency syndrome (AIDS) or AIDS-related complex had a characteristic pattern of T cell deficiency. Abnormally low plasma thymulin levels preceded the development of peripheral blood T cell abnormalities. In contrast to patients with congenital T cell deficiencies, our patients had elevated serum levels of thymosin-alpha 1. Treatment with thymosin fraction 5 in three children with AIDS resulted in only transient clinical and immunologic improvement.
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pubmed:grant |
|
|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0022-3476
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
109
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
422-7
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|
pubmed:dateRevised |
2007-11-14
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|
pubmed:meshHeading |
pubmed-meshheading:3018210-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:3018210-Child,
pubmed-meshheading:3018210-Child, Preschool,
pubmed-meshheading:3018210-Deltaretrovirus,
pubmed-meshheading:3018210-Humans,
pubmed-meshheading:3018210-Infant,
pubmed-meshheading:3018210-T-Lymphocytes,
pubmed-meshheading:3018210-Thymic Factor, Circulating,
pubmed-meshheading:3018210-Thymosin,
pubmed-meshheading:3018210-Thymus Hormones
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|
pubmed:year |
1986
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|
pubmed:articleTitle |
Circulating thymulin and thymosin-alpha 1 activity in pediatric acquired immune deficiency syndrome: in vivo and in vitro studies.
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|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
