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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1986-9-17
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pubmed:abstractText |
We previously reported the cloning and detailed analysis of the integrated hepatitis B virus sequences in a human hepatoma cell line. We report here the integration of at least one of hepatitis B virus at human satellite DNA sequences. The majority of the cellular sequences identified by this satellite DNA were organized as a multimeric composition of a 0.6-kilobase EcoRI fragment. This clone hybridized in situ almost exclusively to the centromeric heterochromatin of chromosomes 1 and 16 and to a lower extent to chromosome 2 and to the heterochromatic region of the Y chromosome. The immediate flanking host sequence appeared as a hierarchy of repeating units which were almost identical to a previously reported human satellite III DNA sequence.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-1142436,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-1251186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-184962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-231109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-2982143,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-2983098,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-2989822,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-2995835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-3926485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6088800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6089197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6116901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6200609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6250073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6250074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6250075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6253158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6267609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6269750,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6269974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6272317,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6276559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6278420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6288257,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6309408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6621688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6801764,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3016335-6961428
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
731-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3016335-Carcinoma, Hepatocellular,
pubmed-meshheading:3016335-Cell Line,
pubmed-meshheading:3016335-Chromosomes, Human,
pubmed-meshheading:3016335-Chromosomes, Human, 1-3,
pubmed-meshheading:3016335-Chromosomes, Human, 16-18,
pubmed-meshheading:3016335-DNA, Satellite,
pubmed-meshheading:3016335-DNA, Viral,
pubmed-meshheading:3016335-Hepatitis B virus,
pubmed-meshheading:3016335-Humans,
pubmed-meshheading:3016335-Liver Neoplasms,
pubmed-meshheading:3016335-Nucleic Acid Hybridization,
pubmed-meshheading:3016335-Recombination, Genetic,
pubmed-meshheading:3016335-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:3016335-Y Chromosome
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pubmed:year |
1986
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pubmed:articleTitle |
Integration of hepatitis B virus DNA in chromosome-specific satellite sequences.
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pubmed:publicationType |
Journal Article
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